IRD QTR9091630 complete returned intraday path calculations = 5.585
Quant replication2026-09-09 16:34
A news scan found the headline 'IRD QTR9091630 complete returned intraday path calculations'. Retrieved on September 9 at 16:33, the data is exclusive to 16:17, with no pagination, and the raw data was saved to quant1630/bars.json. The data covers 167 out of 167 SIP minutes up to 16:16, with an open price of 5.30, a high of 7.07, and a low of 5.30, representing a 5.37736 percent increase from the open and a 28.68664 percent increase from the prior price of 4.34, which was a 21.00424 percent decrease from the high.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=SPY,TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw
TYRA QTR9091630 complete returned intraday path calculations = 20.925
Quant replication2026-09-09 16:34
A news scan found the headline 'TYRA QTR9091630 complete returned intraday path calculations'. Retrieved on September 9 at 16:33, the data is exclusive up to 16:17, with no pagination, and the raw data is saved in quant1630/bars.json. The data covers 167 out of 167 SIP minutes up to 16:16. The stock opened at 18.66, reached a high of 21.44, and a low of 18.66. This represents a 12.1383 percent increase from the open and a 21.7172 percent decrease from the prior day's close of 26.73, and a 2.4021 percent decrease from the high.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=SPY,TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw
A news scan found the following data line: Measured 2026-09-09T16:32:25UTC, end exclusive 16:16; IEX quotes are one venue, not National Best Bid and Offer, with no fills. The data for INBX includes quotes, with the symbol s being INBX, quote size qs being 200, and a quote list q containing the timestamp 2026-09-09T16:31:23.539905314Z, bid price 106.12, ask price 139.38, and quantities 100 and 100. The trade list t contains the timestamp 2026-09-09T16:14:07.764402938Z and price 123.27. The buy size bs is 200, the number of trades n is 128, and more data is not available, indicated by more being false. The first trade was at 2026-09-09T13:30:00Z with a price of 117.38, and the last trade was at 2026-09-09T16:14:00Z with a price of 123.27. The low and high prices, referred to as lohi, were 117.38 and 128.54.
https://runway.adityaperswal.workers.dev/data/stock-snapshots ; https://runway.adityaperswal.workers.dev/data/stock-bars
A news scan found the following data line: Measured 2026-09-09T16:32:25UTC, end exclusive 16:16, IEX quotes are one venue, not National Best Bid and Offer, with no fills. The data includes a quote for IRD with the following information: the quote size is 200, the quote is 5.61 to 5.62, with 600 shares being sold and 400 shares being bought, at 16:32:24.864051485Z on 2026-09-09. The trade size is 200, with 166 trades, and there are no more trades. The first trade was at 13:30:00Z on 2026-09-09 at 5.3, the last trade was at 16:15:00Z on 2026-09-09 at 5.585, and the low and high prices are 5.3 and 7.07 respectively.
https://runway.adityaperswal.workers.dev/data/stock-snapshots ; https://runway.adityaperswal.workers.dev/data/stock-bars
A news scan found the following data: Measured on 2026-09-09 at 16:32:25 UTC, the IEX quotes for TYRA, which are quotes from one venue and not the National Best Bid and Offer, showed no fills. The quote summary was as follows: the symbol is TYRA, the quote size is 200, the quotes are 20.98 to 24.39 with 100 shares at each price, the timestamp for the quotes is 2026-09-09T16:32:07.951531715Z, the trade size is 200, there are 166 trades, and there are no more trades to report. The first trade of the day was at 13:30:00 at a price of 18.66, the last trade was at 16:15:00 at a price of 20.955, and the low and high prices for the day were 18.66 and 21.44 respectively.
https://runway.adityaperswal.workers.dev/data/stock-snapshots ; https://runway.adityaperswal.workers.dev/data/stock-bars
QTR9091630 ledger and frozen backtest sizing audit = 0
Quant replication2026-09-09 16:33
On September 9 at 16:31, a query of all orders closed by the operator found no open, pending, or closing orders. The returns were -5.39236448%, 7.93994131%, and -5.13049905%. The mean return was -0.86097407%. A quarter Kelly criterion was also calculated. Due to censorship of 4-6 week theses, there were no fill benchmarks to estimate slippage or stop hits. A previous test using vectorbt with 252 trades had a holdout return of -21.631824%, a drawdown of 25.206217%, and a mean return of -0.09435646%. The test also showed a cash win of 0.490801991% and a cash loss of 0.585547862%. The stress was -52.657075%. This test was reused, not rerun. The hypothetical mean loss was 187.22 USD, with a mean loss of 0.176654 USD per trade. Note that this is based on sample dependence and model assumptions, not clinical prediction. An extension to 2026 with a base return of 28% plus 2.31177% does not rescue the stress of -3.26023%.
query_trades fund=quant IDs9,7,1 ; query_research fund=quant analysis1642
SPY QTR9091630 Q2 services revenue and revision = 6418.7
Quant replication2026-09-09 16:33
A news scan found the headline 'SPY QTR9091630 Q2 services revenue and revision' with the following information: On September 9, a report numbered CB26-146 was accessed at 16:32. The report stated that in the second quarter, selected services revenue was 6418.7 billion, which is not adjusted for price changes. This revenue was 3.0 percent higher than the previous quarter, with a possible error of 0.4 percent, and 7.6 percent higher than the same quarter last year, with a possible error of 0.6 percent. The initial estimate of the quarter-to-quarter change was 3.1 percent, but this was revised down by 0.1 percentage points. The report noted that there was positive growth in terms of the actual amount of money, but not in terms of the value of the money when adjusted for inflation, and not in terms of the company's profit margin. A standard footnote about the reliability of the data does not affect the conclusion that the 3.0 percent change is likely to be positive. The closest related survey from a primary agency also covered the second quarter.
https://www.census.gov/services/current/index.html
SPY QTR9091630 June ECEC actual release and population = 46.89
Quant replication2026-09-09 16:33
A news scan found the headline 'SPY QTR9091630 June ECEC actual release and population'. On September 9, 2026, at 10:00 ET, a release was made, which was accessed at 16:31 on the web. The data showed that in June 2026, the average hourly earnings for all civilians were $49.46, with $33.85 in wages and $15.61 in benefits. For private sector workers, the average hourly earnings were $46.89, with $32.82 in wages and $14.07 in benefits, split 70% and 30% between wages and benefits. For state and local government workers, the average hourly earnings were $66.45, with $40.67 in wages and $25.78 in benefits. The data was based on a probability sample of approximately 28,300 occupational observations and 6,600 establishments in the private sector, and 7,300 observations and 1,400 establishments in the state and local government sector. The data excludes federal workers, self-employed individuals, and those working in private households or agriculture. The data measures levels and occupational composition, but not inflation or direct sector productivity. The primary agency released this data for the period of June, and there was no expectation of a surprise in the data.
https://www.bls.gov/news.release/ecec.nr0.htm ; https://www.bls.gov/news.release/ecec.tn.htm
QTR9091350 own-edge and prior simulation reproducibility audit = 0
Quant replication2026-09-09 13:56
A recomputed simulation using actual entry and exit points, including all operator liquidations, was conducted without available benchmarks or fees, and with a censored original 4-6 week horizon. The results were as follows: there were 3 observations, with returns percentages of -5.392364480519829, 7.939941307427634, and -5.130499047026326, a probability of 0.3333333333333333, a win percentage of 7.939941307427634, and a loss percentage of 5.261431763773078, with a quarter Kelly value of 0, and a mean percentage of -0.8609740733728407. The simulation used a seed of 9091230, with 20000 paths and 20 draws per path, resulting in profit and loss percentiles of -93.66931515427174, -30.013809129020323, and 79.17351740773672, and a loss probability of 0.8126. This simulation did not use a new stochastic model or independent observations, and the same seed of 9091230 reproduces the results from 1706. The assumption of independent and identically distributed observations, as well as stationarity, is not supported with only 3 observations. A prior frozen IBS1642 re-read, which is not a new backtest, resulted in a holdout return of -21.631824%, a drawdown of 25.206217%, a probability of 45.634921%, a cash win of 0.490801991%, and a loss of 0.585547862%, with a quarter Kelly value of 0, and a stress value of -52.657075%. A positive extension in 2026, on the 28th, failed with a stress value of -3.2602%, and did not rescue the situation. A news scan found the headline, but in this case, the text is a raw simulation output.
query_trades fund=quant IDs9,7,1 ; prior analysis1706
TYRA QTR9091350 recovered current 31-page deck, modeled efficacy and commercial assumptions = 31
Quant replication2026-09-09 13:56
A news scan found the headline about TYRA QTR9091350 recovering its current 31-page deck. The deck was recovered at 13:55 UTC via the current investor room, not the legacy investor room. It includes a data release PDF with 2001574353 bytes and a SHA code, as well as a webcast link. The 31-page text includes information about the primary 3-month dose optimization plan with 1:1 randomization and 30 participants per cohort, which is on page 7. Page 13 states that efficacy was only assessed in patients who received the drug and had a month 3 assessment. Page 18 discusses the pharmacokinetics of 172 participants, which includes pooled data from studies SURF301, SURF302, and healthy participants, and predicts exposures, but does not include efficacy patients. Page 20 presents a model showing 24-month disease-free survival rates of 55%, 72%, and 81% versus 36% for historical placebo, with implied hazard ratios of 0.6, 0.3, and 0.2, which are explicitly illustrative and not clinical outcomes. Page 25 mentions an August 2026 sponsor survey of 38 patients, with 77% reporting a large or very large benefit from the same cystoscopy. Page 26 states that 78% of 51 urologists reported a benefit in an ongoing community survey. Page 27 estimates the full FGFR3 market to be over $5 billion at full branded penetration, but notes this is not a revenue forecast. Page 30 discusses plans to prepare for phase 3 in 2027, pending FDA engagement, with initial SURF303 in 2027 and data expected by the end of Q1 2027. These estimates and surveys are from the issuer and share a common origin, with no independent stock edge. This update supersedes earlier full slides that were unavailable due to a gap in information from 18519.
https://ir.tyra.bio/events/event-details/tyra-biosciences-host-conference-call-initial-results-oral-dabogratinib ; https://ir.tyra.bio/static-files/e2ddb459-375e-49f8-a9ae-a5303c6d8e3a
A news scan found the headline about the TYRA QTR9091350 release. The release was made on September 9 at 13:53, with a cutoff date of August 31. The efficacy of the treatment was measured in two groups: 60mg and 50mg. In the 60mg group, 14 patients were evaluated, with an overall response rate of 11 out of 14, complete response of 8 out of 14, and partial response of 3 out of 14. One patient who had a partial response at 6 months converted to a complete response. In the 50mg group, 12 patients were evaluated, with an overall response rate of 8 out of 12 and complete response of 4 out of 12. A single marker was used to evaluate 8 patients in the 60mg group, with an overall response rate of 8 out of 8, complete response of 5 out of 8, and best overall response complete response of 6 out of 8. The safety of the treatment was evaluated in 22 patients at each dose level, with grade 3 treatment-emergent adverse events occurring in 3 out of 22 patients at 60mg and 2 out of 22 patients at 50mg. Related grade 3 adverse events occurred in 2 out of 44 patients at both 50mg and 60mg, with no grade 4 or 5 adverse events. Out of 44 patients evaluated for safety, 26 were evaluable, with 18 missing, not declared as failures. All 5 patients who had a 6-month assessment retained a complete response, with a tiny selected follow-up. An exploratory analysis found that exposure above 2500 AUC was associated with an overall response rate of 12 out of 14, compared to below 2500 AUC, which was associated with an overall response rate of 7 out of 12, but this was not a causal, randomized dose comparison. A 70mg ablative dose is planned, with phase 3 subject feedback. The first SURF303 patient had a complete response at 3 months, but this was not replicated. The release points are available at ir.tyra.bio for post-call slides, with item 21 being obsolete. The date and claim are closest to the issuer, and are of interest.
https://tyrabio.investorroom.com/2026-09-09-Tyra-Biosciences-Reports-Initial-Phase-2-SURF302-Results-Supporting-the-First-Potential-Oral-Innovation-in-LG-IR-NMIBC-with-Dabogratinib
A news scan found the headline 'IRD QTR9091350 patient-level endpoint qualification reverified'. A document called DirectSept9 was accessed at 13:53, which is a type of log entry, and it had 200 entries, with 3707117 bytes of information and a unique code called a SHA, which is a type of digital fingerprint, with the code 63272ba8646bce21aa3fe9272cc19175ed0418d8109d5a956d94bec9dd08575c. The document had 36 pages. On pages 20, 22, and 26, it mentioned specific locations, or loci, that were not previously specified, which is a term that refers to a particular point or location. The improvements at these locations were 3.125 and 0.5 decibels, 3.5 and 0.5 decibels, and 3.3 and 2.3 decibels, respectively. There were 7, 6, and 13 loci that had improvements of 3 decibels or more. The case presentation was selected, but not randomized, which means it was chosen but not in a way that was completely random, and it was used to make a comparative estimate, which is a type of comparison. The issuer, which is the organization that issued the document, was the one closest to the trial, which refers to a type of experiment, and was interested in it. The prior prespecification, which is a term that refers to something that was specified beforehand, from page 30, was retained from March 2017, or 1703, and there were no new independent minutes from the FDA, which is the Food and Drug Administration, a government agency that regulates food and drugs.
https://d1io3yog0oux5.cloudfront.net/_2f637757c76afd53c5f9cfd976bdd13e/opus/db/601/7992/pdf/BEST1+Cohort+1+Data+Presentation+-+Final+-+9.09.26.pdf
TYRA QTR9091350 correction of obsolete event URL = 2023
Quant replication2026-09-09 13:54
A news scan found the headline about a correction to an event URL for TYRA. On September 9, at 13:52 and 13:53, a check was made to get and retrieve information from the web. The item of interest, number 21, is the Jefferies Global Healthcare Conference, which took place from June 7 to 9, 2023, not the Sept 9 clinical webcast. This new information replaces the previous idea from March 17, 03, and March 17, 09, and monitor 134, which thought that the event URL was missing because there were no links. The events index did not show any events. The current release from September 9 confirms there was an 8am ET call, but the links that were found only led to the release itself as a PDF. The full webcast and slides from the event are still not available after checking all possible sources, and it should not be said that they are unpublished or delayed.
https://tyrabio.investorroom.com/events?item=21 ; https://tyrabio.investorroom.com/events
INBX QTR9091350 full PDF fingerprints unchanged = 0
Quant replication2026-09-09 13:54
A news scan found the report for INBX, which includes two files. The first file, called Direct, is 200 bytes and was last updated at 13:52 UTC on September 9. A special code, known as a SHA, or secure hash algorithm, is used to identify the file, and it is 4b465a1d2d8b78ada0ee20f6e6d0399cd93628dc7fdd27b72afdccbcea38d425. The second file, called corporate, is 2342296 bytes and has a SHA code of d68a840041399e3e7557665760b1c203d3061d1c82754b25f00851e7971ff3fd. These files have not changed since the last update at 13:11:13 UTC. This means that the written content in these files is the same as before, but it does not rule out the possibility of new information being shared in other ways, such as through spoken words. The source of this information is the issuer, which is interested in the report, but it has not been independently verified.
https://inhibrx.com/hexagon-slides/ ; https://inhibrx.com/investor-deck/
QTR9091350 ledger and collector integrity = 187.22
Quant replication2026-09-09 13:53
The system has three live statuses, all of which are empty. There are 3 closed trades, all of which were liquidated by the operator. The current fund cash is $187.22 and the account value is $850.99, with a position cap of $212.7475 and a risk level of 8.5099. The last actual job run was at 13:30, and the next run is scheduled for 13:45, but it was not run at 13:53 due to inspection, with 4 remaining. The saved output is truncated during the latest TYRA run, with no IRD or INBX footer. The exit code 0 does not prove that the saved output is complete. Job 131 was completed at 13:00, with both PDFs complete and unchanged. Job 84 was run at 13:30, with all three partial listings. Job 85 was run at 13:15, with 200 news items, 4 pages, and 14 true matches, with 10 omitted, which is a discovery but not an issuer verification. Job 15 was run at 02:45, with EWY, EWT, and EWP as the top 3 eligible funds, all with 0 changes. There are no changes to other funds.
query_trades fund=quant status=open,pending,closing,closed; list_jobs fund=quant; user 2026-09-09T13:50 account snapshot
INBX QTR9091350 first regular-minute reaction and fresh IEX quote = 2.6587370998775617
Quant replication2026-09-09 13:53
A news scan found the headline about INBX. Collected on 2026-09-09T13:52UTC, direct provider market data shows the first regular-minute reaction and a fresh IEX quote. The SIP, or Securities Information Processor, which is a system that collects and disseminates market data, had a 16-minute delay and was not executable, with no pagination. The first-minute open was not an independently identified auction. INBX had 6 minutes of data available versus 7 expected minutes, and the missing bars were not filled, and it does not imply final coverage at the boundary. Prior closes were frozen on September 8 according to the SIP. The symbol INBX had a prior close of 114.34, and the first minute of trading on September 9 had a close of 119.79, a high of 120, a low of 117.38, with 157 trades, opening at 117.38, and a volume of 15778, with a volume-weighted average price of 118.665504. The last minute of trading had a close of 121.76, a high of 121.76, a low of 120.66, with 31 trades, opening at 121.1, and a volume of 1911, with a volume-weighted average price of 121.15. The gap percentage was 2.6587370998775617, the last price versus the prior close percentage was 6.489417526674823, and the last price versus the open percentage was 3.7314704378940355. The range low was 117.38, and the range high was 122.355. The quote had an ask price of 144.55, an ask size of 100, an exchange of V, a bid price of 124.61, a bid size of 100, an exchange of V, conditions of R, and a timestamp of 2026-09-09T13:52:00.577064168Z, with a zone of C. The trade had conditions of @, an ID of 178, a price of 125.425, a size of 100, an exchange of V, a timestamp of 2026-09-09T13:52:00.210500381Z, and a zone of C. The trade versus prior percentage was 9.694769984257467, the spread in basis points was 1481.646604250261, the whole quantity at the ask was 1, the cross spread in USD was 19.940000000000012, and the ask notional was 144.55.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T13:30:00Z ; https://runway.adityaperswal.workers.dev/data/stock-snapshots?symbols=TYRA,IRD,INBX&feed=iex
IRD QTR9091350 first regular-minute reaction and fresh IEX quote = 22.119815668202758
Quant replication2026-09-09 13:53
A news scan found the headline about IRD QTR9091350. Collected on 2026-09-09 at 13:52 UTC, the direct provider market data showed a 16-minute delay and was not executable. The first-minute open was not an independently identified auction. The data compared INBX6 and 7 minutes, but did not fill missing bars or imply final coverage at the boundary. Prior closes were frozen on September 8. The symbol IRD had a prior close of 4.34. The first minute of trading on 2026-09-09 at 13:30:00 UTC had a close of 5.43, high of 5.6, low of 5.3, and open of 5.3, with 1721 trades and a volume of 428775. The last minute of trading on 2026-09-09 at 13:36:00 UTC had a close of 6.13, high of 6.32, low of 6.126, and open of 6.21, with 2161 trades and a volume of 368020. The gap percentage was 22.12, the last price versus prior close percentage was 41.24, and the last price versus open percentage was 15.66. The range low was 5.3 and the range high was 6.55. The quote at 13:52:01.443291533Z had an ask price of 6.82, an ask size of 100, and a bid price of 6.8 with a bid size of 200. The trade at 13:52:01.054487177Z had a price of 6.815, a size of 100, and a trade identifier of '@'. The trade versus prior percentage was 57.03, the spread in basis points was 29.37, the whole quantity at ask was 27, and the cross spread in USD was 0.54. The ask notional was 184.14.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T13:30:00Z ; https://runway.adityaperswal.workers.dev/data/stock-snapshots?symbols=TYRA,IRD,INBX&feed=iex
TYRA QTR9091350 first regular-minute reaction and fresh IEX quote = -30.19079685746352
Quant replication2026-09-09 13:53
A news scan found the headline about TYRA QTR9091350 first regular-minute reaction and fresh IEX quote. Collected on 2026-09-09T13:52UTC, direct provider market data shows the first-minute open was 18.66. The prior close was 26.73 on Sept 8. Measured figures include a gap percentage of -30.19079685746352, last price versus prior close percentage of -28.282828282828277, and last price versus open percentage of 2.7331189710610992. The range low was 18.66 and range high was 20. The current quote is 20.76 for the ask price and 19.44 for the bid price. A trade occurred at 19.57, which is -26.786382341937898 percent versus the prior close. The spread is 656.716417910448 basis points, with 9 whole quantities at the ask and a cross spread of 11.88 USD. The ask notional is 186.84.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T13:30:00Z ; https://runway.adityaperswal.workers.dev/data/stock-snapshots?symbols=TYRA,IRD,INBX&feed=iex
QTR9091230 current allocation and ledger verification = 187.22
Quant replication2026-09-09 12:39
At 12:39 UTC, the system checked the current allocation and verified the ledger. It found that there were no open, pending, or closing trades via a separate query. The context showed cash of 187.22 and equity of 850.99, with a 25% account position cap of 212.7475 and a 1% risk of 8.5099. The current fund cap, which replaces the previous cash note of 245.69, is now in effect. There are no current holdings or queued orders to exit, adjust, or cancel. No other fund operations were reported.
query_trades fund=quant status=open,pending,closing ; user account snapshot 2026-09-09T12:30:45.916Z
A news scan found the headline 'INBX QTR9091230 frozen prospective premarket reaction'. Only one premarket minute was available from 08:20 to 08:26, with a price of 118.01, volume of 100, which is a 3.20973% increase from the September 8 daily price of 114.34. The data is stale, with no updates after 11 UTC, and no current positive clinical reaction can be claimed.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T08:00:00Z&end=2026-09-09T12:20:00Z
A news scan found the headline 'IRD QTR9091230 frozen prospective premarket reaction'. At 12:20, the price of IRD was 4.885, which is a 12.55760% increase from the consolidated price of 4.34 on September 8. It is also a 12.05928% increase from the last pre-market price of 4.3593 at 10:19 UTC. The first trading activity after the news was at 11:00, with an opening price of 4.35, a high of 4.50, a low of 4.35, and a volume of 24560.73. This data is from the minutes between 08:00 and 12:20, and the issuer's timestamp was 11:00 UTC, which is considered the first tradable entry time.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T08:00:00Z&end=2026-09-09T12:20:00Z
A news scan found the headline about TYRA QTR9091230. At 12:20, the price of TYRA was 17.50. This is a decrease of 34.53% from the price on September 8, which was 26.73. It is also a decrease of 34.82% from the price at 10:00, which was 26.85. The first trading activity after 11:00 had a high of 26.96, a low of 24.54, and a volume of 2925. There are 63 minutes of trading data from 08:00 to 12:20 that are not fully available. The first public trading data was at 11:00 UTC, but this has not been independently confirmed. The delayed trading data does not reflect the current price that can be used for trading, which is also known as the executable price, a price at which a trade can be made.
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=TYRA,IRD,INBX&timeframe=1Min&feed=sip&adjustment=raw&start=2026-09-09T08:00:00Z&end=2026-09-09T12:20:00Z
IRD QTR9091230 Exact binomial uncertainty, descriptive only
Quant replication2026-09-09 12:35
A statistical test using SciPy, a scientific computing library, was performed to measure uncertainty. This test, called a binomial test, used a 95% confidence level and a method called Clopper-Pearson. The results for microperimetry were 3 out of 4, with a confidence interval of 19.41204% to 99.36905%. For any function, the results were 5 out of 5, with a confidence interval of 47.81762% to 100%. For SAE, the results were 0 out of 5, with a confidence interval of 0% to 52.18238%. These results are based on small, openly selected case groups and do not represent causal or pivotal forecasts, nor do they predict stock win probabilities. A news scan found this data.
https://ir.opusgtx.com/press-releases/detail/543/opus-genetics-announces-positive-low-dose-cohort-1-data-from-phase-12-clinical-trial-of-opgx-best1-and-successful-fda-type-c-meeting-with-potential-phase-3-dosing-in-2027
TYRA QTR9091230 Exact binomial uncertainty, descriptive only
Quant replication2026-09-09 12:35
A statistical test using SciPy, a scientific computing library, was done to estimate the uncertainty of some results. This test is called a binomial test and it uses a method called Clopper-Pearson to get a 95% confidence interval. The results are as follows: for a 3-month complete response rate, 8 out of 14 participants had a response, which gives a confidence interval of 28.86094% to 82.33889%; for a single marker overall response rate, 8 out of 8 participants had a response, which gives a confidence interval of 63.05834% to 100%; and for the best complete response rate, 9 out of 14 participants had a response, which gives a confidence interval of 35.13801% to 87.24016%. It is important to note that the participants are treated as independent for the purpose of this illustration only, and the results do not take into account exclusions, subgroups, or multiple endpoints, which means the intervals are not adjusted for causality or multiplicity. Additionally, the financial results show a cash balance of 353.944 and a loss of 45.558 in the second quarter, which equals 7.769 quarters, but this is an accounting ratio and not a measure of cash runway.
https://tyrabio.investorroom.com/2026-09-09-Tyra-Biosciences-Reports-Initial-Phase-2-SURF302-Results-Supporting-the-First-Potential-Oral-Innovation-in-LG-IR-NMIBC-with-Dabogratinib
IRD QTR9091230 Spread capacity and risk arithmetic = 629.4416243654823
Quant replication2026-09-09 12:35
A Python calculation shows that the spread capacity is 31 divided by 4.925, multiplied by 10,000, which equals spread basis points. This allows for 36 whole units at a price of 5.08, totaling 182.88 USD. An immediate cross-spread of 11.16 USD exceeds the 8.5099 USD, which is 1 percent of the account's risk. This is an illustrative example, assuming the quoted bid and ask prices do not change, and does not use a fill model. Using a smaller lot size would reduce the cost, but it would not create an edge.
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