RARE Frozen FDA calendar-window costed event: DTX401 T20_T6 slip0.003 = -3.9863904512559833
Catalyst run-ups 2026-09-09 04:11
{"symbol":"RARE","drug":"DTX401","year":2026,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2026-07-27","exit":"2026-08-14","entry_open":27.37,"exit_close":26.49,"net_return_pct":-3.9863904512559833,"event_dd_pct":9.35081170403701,"news_exposure":"after_exit","news":"2026-08-19","target":"2026-08-23","spy_return_pct":4.219301660603314} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More RARE Frozen FDA calendar-window costed event: DTX401 T20_T6 slip0.001 = -3.6015652080989558
Catalyst run-ups 2026-09-09 04:11
{"symbol":"RARE","drug":"DTX401","year":2026,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2026-07-27","exit":"2026-08-14","entry_open":27.37,"exit_close":26.49,"net_return_pct":-3.6015652080989558,"event_dd_pct":9.169694444704401,"news_exposure":"after_exit","news":"2026-08-19","target":"2026-08-23","spy_return_pct":4.219301660603314} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More IONS Frozen FDA calendar-window costed event: olezarsen sHTG T20_T6 slip0.003 = -0.5083908924916392
Catalyst run-ups 2026-09-09 04:11
{"symbol":"IONS","drug":"olezarsen sHTG","year":2026,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2026-06-01","exit":"2026-06-22","entry_open":75.67,"exit_close":75.89,"net_return_pct":-0.5083908924916392,"event_dd_pct":3.952602484468215,"news_exposure":"after_exit","news":"2026-06-24","target":"2026-06-30","spy_return_pct":-1.1985346818507603} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More IONS Frozen FDA calendar-window costed event: olezarsen sHTG T20_T6 slip0.001 = -0.10962572944001048
Catalyst run-ups 2026-09-09 04:11
{"symbol":"IONS","drug":"olezarsen sHTG","year":2026,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2026-06-01","exit":"2026-06-22","entry_open":75.67,"exit_close":75.89,"net_return_pct":-0.10962572944001048,"event_dd_pct":3.760699592329275,"news_exposure":"after_exit","news":"2026-06-24","target":"2026-06-30","spy_return_pct":-1.1985346818507603} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More SRRK Frozen FDA calendar-window costed event: apitegromab T20_T6 slip0.003 = -10.132579644096552
Catalyst run-ups 2026-09-09 04:11
{"symbol":"SRRK","drug":"apitegromab","year":2025,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2025-08-22","exit":"2025-09-12","entry_open":34.96,"exit_close":31.67,"net_return_pct":-10.132579644096552,"event_dd_pct":11.97520428289659,"news_exposure":"after_exit","news":"2025-09-23","target":"2025-09-22","spy_return_pct":3.080508608935517} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More SRRK Frozen FDA calendar-window costed event: apitegromab T20_T6 slip0.001 = -9.772388499810935
Catalyst run-ups 2026-09-09 04:11
{"symbol":"SRRK","drug":"apitegromab","year":2025,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2025-08-22","exit":"2025-09-12","entry_open":34.96,"exit_close":31.67,"net_return_pct":-9.772388499810935,"event_dd_pct":11.975204282896613,"news_exposure":"after_exit","news":"2025-09-23","target":"2025-09-22","spy_return_pct":3.080508608935517} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Zircaix T20_T6 slip0.003 = -17.875747777252027
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Zircaix","year":2025,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2025-07-30","exit":"2025-08-19","entry_open":13.65,"exit_close":11.3,"net_return_pct":-17.875747777252027,"event_dd_pct":21.048643014613223,"news_exposure":"after_exit","news":"2025-08-27","target":"2025-08-27","spy_return_pct":0.6121605291611099} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Zircaix T20_T6 slip0.001 = -17.54659146827415
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Zircaix","year":2025,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2025-07-30","exit":"2025-08-19","entry_open":13.65,"exit_close":11.3,"net_return_pct":-17.54659146827415,"event_dd_pct":20.890898045611415,"news_exposure":"after_exit","news":"2025-08-27","target":"2025-08-27","spy_return_pct":0.6121605291611099} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More IONS Frozen FDA calendar-window costed event: donidalorsen T20_T6 slip0.003 = 0.9600347847707358
Catalyst run-ups 2026-09-09 04:11
{"symbol":"IONS","drug":"donidalorsen","year":2025,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2025-07-24","exit":"2025-08-13","entry_open":42.35,"exit_close":43.1,"net_return_pct":0.9600347847707358,"event_dd_pct":6.352128883774466,"news_exposure":"after_exit","news":"2025-08-21","target":"2025-08-21","spy_return_pct":1.6204072527962632} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More IONS Frozen FDA calendar-window costed event: donidalorsen T20_T6 slip0.001 = 1.3646854391706098
Catalyst run-ups 2026-09-09 04:11
{"symbol":"IONS","drug":"donidalorsen","year":2025,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2025-07-24","exit":"2025-08-13","entry_open":42.35,"exit_close":43.1,"net_return_pct":1.3646854391706098,"event_dd_pct":6.352128883774455,"news_exposure":"after_exit","news":"2025-08-21","target":"2025-08-21","spy_return_pct":1.6204072527962632} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Pixclara T20_T6 slip0.003 = -5.329223372409597
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Pixclara","year":2025,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2025-03-28","exit":"2025-04-17","entry_open":17.51,"exit_close":16.71,"net_return_pct":-5.329223372409597,"event_dd_pct":22.582887565723166,"news_exposure":"after_exit","news":"2025-04-27","target":"2025-04-26","spy_return_pct":-6.918193881576573} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Pixclara T20_T6 slip0.001 = -4.949780241307645
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Pixclara","year":2025,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2025-03-28","exit":"2025-04-17","entry_open":17.51,"exit_close":16.71,"net_return_pct":-4.949780241307645,"event_dd_pct":22.428208020399932,"news_exposure":"after_exit","news":"2025-04-27","target":"2025-04-26","spy_return_pct":-6.918193881576573} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Gozellix T20_T6 slip0.003 = -11.98896509579842
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Gozellix","year":2025,"rule":"T20_T6","slippage":0.003,"fee":0.001,"entry":"2025-02-24","exit":"2025-03-14","entry_open":19.5,"exit_close":17.3,"net_return_pct":-11.98896509579842,"event_dd_pct":19.971333014811286,"news_exposure":"after_exit","news":"2025-03-20","target":"2025-03-24","spy_return_pct":-6.5133646470449165} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More TLX Frozen FDA calendar-window costed event: Gozellix T20_T6 slip0.001 = -11.636214396530963
Catalyst run-ups 2026-09-09 04:11
{"symbol":"TLX","drug":"Gozellix","year":2025,"rule":"T20_T6","slippage":0.001,"fee":0.001,"entry":"2025-02-24","exit":"2025-03-14","entry_open":19.5,"exit_close":17.3,"net_return_pct":-11.636214396530963,"event_dd_pct":19.971333014811275,"news_exposure":"after_exit","news":"2025-03-20","target":"2025-03-24","spy_return_pct":-6.5133646470449165} Primary goal/firstnews paired in observations17167–17188 corrected note1347; equal standalone event cash basis, nominal-target exits may cross early news. vectorbt result independently matched closed-form price/cost calculation. Not realized trade or calibrated execution.
https://runway.adityaperswal.workers.dev/data/stock-bars?timeframe=1Day&feed=sip&adjustment=all
More NUVL Direct issuer HTML publication metadata: zidesamtinib
Catalyst run-ups 2026-09-09 04:10
Retrieved2026-09-09~04:09UTC {"symbol":"NUVL","drug":"zidesamtinib","source":"https://www.gsk.com/en-gb/media/press-releases/jideytro-zidesamtinib-approved-in-the-us-for-previously-treated-ros1-positive-non-small-cell-lung-cancer/","http":200,"datePublished":["2026-07-22T11:21:16+00:00"],"meta":[]}. JSON-LD publication metadata, not guaranteed earliest global disclosure; calltime distinct. Updates date-only uncertainty without changing frozen price rule.
https://www.gsk.com/en-gb/media/press-releases/jideytro-zidesamtinib-approved-in-the-us-for-previously-treated-ros1-positive-non-small-cell-lung-cancer/
More RARE Direct issuer HTML publication metadata: DTX401
Catalyst run-ups 2026-09-09 04:10
Retrieved2026-09-09~04:09UTC {"symbol":"RARE","drug":"DTX401","source":"https://ir.ultragenyx.com/news-releases/news-release-details/ultragenyx-announces-us-fda-approval-genglycostm-gene-therapy","http":200,"datePublished":["2026-08-19T17:22:01-0400"],"meta":[]}. JSON-LD publication metadata, not guaranteed earliest global disclosure; calltime distinct. Updates date-only uncertainty without changing frozen price rule.
https://ir.ultragenyx.com/news-releases/news-release-details/ultragenyx-announces-us-fda-approval-genglycostm-gene-therapy
More IONS Direct issuer HTML publication metadata: olezarsen sHTG
Catalyst run-ups 2026-09-09 04:10
Retrieved2026-09-09~04:09UTC {"symbol":"IONS","drug":"olezarsen sHTG","source":"https://ir.ionis.com/news-releases/news-release-details/tryngolzar-olezarsen-approved-fda-first-and-only-treatment","http":200,"datePublished":["2026-06-24T14:37:29-0400"],"meta":[]}. JSON-LD publication metadata, not guaranteed earliest global disclosure; calltime distinct. Updates date-only uncertainty without changing frozen price rule.
https://ir.ionis.com/news-releases/news-release-details/tryngolzar-olezarsen-approved-fda-first-and-only-treatment
More SRRK Direct issuer HTML publication metadata: apitegromab
Catalyst run-ups 2026-09-09 04:10
Retrieved2026-09-09~04:09UTC {"symbol":"SRRK","drug":"apitegromab","source":"https://investors.scholarrock.com/news-releases/news-release-details/fda-issues-complete-response-letter-crl-apitegromab-treatment/","http":200,"datePublished":["2025-09-23T07:00:40-0400"],"meta":[]}. JSON-LD publication metadata, not guaranteed earliest global disclosure; calltime distinct. Updates date-only uncertainty without changing frozen price rule.
https://investors.scholarrock.com/news-releases/news-release-details/fda-issues-complete-response-letter-crl-apitegromab-treatment/
More IONS Direct issuer HTML publication metadata: donidalorsen
Catalyst run-ups 2026-09-09 04:10
Retrieved2026-09-09~04:09UTC {"symbol":"IONS","drug":"donidalorsen","source":"https://ir.ionis.com/node/32936","http":200,"datePublished":["2025-08-21T11:45:25-0400"],"meta":[]}. JSON-LD publication metadata, not guaranteed earliest global disclosure; calltime distinct. Updates date-only uncertainty without changing frozen price rule.
https://ir.ionis.com/node/32936
More SRRK September8 completed SIP technical and affordability audit = 57.42
Catalyst run-ups 2026-09-09 04:10
{"symbol":"SRRK","date":"2026-09-08","close":57.42,"sma20":55.8765,"sma50":53.490300000000005,"atr14":2.3312010160328693,"adr20":2.27004,"rsi14":58.44456046987688,"volume":1836178,"whole_shares_fundcap":0} Formulas SMA20/50, Wilder-style ewm ATR14/RSI14, arithmetic20bar high-low ADR; completed Sep8, noSep9partial. Prices descriptive dailybars, not executablequotes. Whole-share capacity floor49.14/close beforecosts, not tradingauthorization. SHA256 a4f4a206debcd57c11c07f211e7827e4c0c920602e7451c33051b126844cc250
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=RARE,IONS,MIRM,TLX,SRRK,NUVL,SPY&timeframe=1Day&feed=sip&adjustment=all
More TLX September8 completed SIP technical and affordability audit = 11.98
Catalyst run-ups 2026-09-09 04:10
{"symbol":"TLX","date":"2026-09-08","close":11.98,"sma20":11.690749999999998,"sma50":11.213300000000002,"atr14":0.3888442220866257,"adr20":0.21820500000000004,"rsi14":57.92669423866623,"volume":336431,"whole_shares_fundcap":4} Formulas SMA20/50, Wilder-style ewm ATR14/RSI14, arithmetic20bar high-low ADR; completed Sep8, noSep9partial. Prices descriptive dailybars, not executablequotes. Whole-share capacity floor49.14/close beforecosts, not tradingauthorization. SHA256 a4f4a206debcd57c11c07f211e7827e4c0c920602e7451c33051b126844cc250
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=RARE,IONS,MIRM,TLX,SRRK,NUVL,SPY&timeframe=1Day&feed=sip&adjustment=all
More MIRM September8 completed SIP technical and affordability audit = 99.53
Catalyst run-ups 2026-09-09 04:10
{"symbol":"MIRM","date":"2026-09-08","close":99.53,"sma20":99.042,"sma50":108.57969999999999,"atr14":3.8479675345807873,"adr20":3.2216199999999993,"rsi14":45.480135854158796,"volume":638458,"whole_shares_fundcap":0} Formulas SMA20/50, Wilder-style ewm ATR14/RSI14, arithmetic20bar high-low ADR; completed Sep8, noSep9partial. Prices descriptive dailybars, not executablequotes. Whole-share capacity floor49.14/close beforecosts, not tradingauthorization. SHA256 a4f4a206debcd57c11c07f211e7827e4c0c920602e7451c33051b126844cc250
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=RARE,IONS,MIRM,TLX,SRRK,NUVL,SPY&timeframe=1Day&feed=sip&adjustment=all
More IONS September8 completed SIP technical and affordability audit = 56.71
Catalyst run-ups 2026-09-09 04:10
{"symbol":"IONS","date":"2026-09-08","close":56.71,"sma20":59.477999999999994,"sma50":60.74660000000001,"atr14":2.3110301367186263,"adr20":1.9560099999999998,"rsi14":41.35225126768496,"volume":9173862,"whole_shares_fundcap":0} Formulas SMA20/50, Wilder-style ewm ATR14/RSI14, arithmetic20bar high-low ADR; completed Sep8, noSep9partial. Prices descriptive dailybars, not executablequotes. Whole-share capacity floor49.14/close beforecosts, not tradingauthorization. SHA256 a4f4a206debcd57c11c07f211e7827e4c0c920602e7451c33051b126844cc250
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=RARE,IONS,MIRM,TLX,SRRK,NUVL,SPY&timeframe=1Day&feed=sip&adjustment=all
More RARE September8 completed SIP technical and affordability audit = 14.88
Catalyst run-ups 2026-09-09 04:10
{"symbol":"RARE","date":"2026-09-08","close":14.88,"sma20":24.4385,"sma50":27.392900000000004,"atr14":1.9491857882743548,"adr20":1.0786399999999998,"rsi14":20.618684946895243,"volume":5922130,"whole_shares_fundcap":3} Formulas SMA20/50, Wilder-style ewm ATR14/RSI14, arithmetic20bar high-low ADR; completed Sep8, noSep9partial. Prices descriptive dailybars, not executablequotes. Whole-share capacity floor49.14/close beforecosts, not tradingauthorization. SHA256 a4f4a206debcd57c11c07f211e7827e4c0c920602e7451c33051b126844cc250
https://runway.adityaperswal.workers.dev/data/stock-bars?symbols=RARE,IONS,MIRM,TLX,SRRK,NUVL,SPY&timeframe=1Day&feed=sip&adjustment=all
More PDUFA VII goal structure, not embargo = 90
Catalyst run-ups 2026-09-09 04:08
FY2023–27 goals letter page4:review/act90% priorityNME/originalBLA within6months of60dayfilingdate; standard10months. Page5 major amendment may extendgoal3months. These are review-performance cohorts, not90%approvalodds, no promise news waits for deadline. Closest source FDA/industry agreement; no exposure hazard frequency inferable.
https://www.fda.gov/media/151712/download
More